Oral Medications

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Oral medications include:

Aubagio (teriflunomide) is a once a day medication that decreases inflammation and reduces the risk of worsening disability.

Mavenclad (cladribine) is taken for only 4-5 days four times over 4 years which results in resetting of the immune system.

Fumarates are taken twice a day to prevent relapses, worsening disability and new MRI activity.  Treatments include Tecfidera (dimethyl fumarate), Vumerity (diroximel fumarate) and Bafiertam (monomethyl fumarate).

S1P (sphingosine-1-phosphate receptor modulator) medications are taken once a day to prevent relapses and worsening disability.  This class includes Gilenya (fingolimod), Mayzent (siponimod), Ponvory (ponesimod) and Zeposia (ozanimod). Mayzent was shown to be effective in secondary-progressive disease.