Archive for ‘MS Center News

Mar 21 2016 Join Team MoBap for Walk MS April 17

Curing MS and repairing disease damage requires innovative, groundbreaking research. Funding for research is critical.  That’s why we need YOU!

Support the National Multiple Sclerosis Society by joining or donating to Team MoBap.  STAFF, PATIENTS, FRIENDS and FAMILY ARE INVITED on our team.

Walk MS is Sunday April 17 2016 at Forest Park Upper Muny Lot.  Registration 1 PM, Start 2 PM.


GATEWAYWALKMS.ORG | 1-800-344-4867


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Sep 8 2015 YOU are invited! Our Annual Update: Groundbreaking MS News

Join us for The MS Center for Innovation in Care’s annual program focused on the latest updates in multiple sclerosis.  The meeting takes place right after the largest global MS meeting called ECTRIMS in Barcelona, Spain in October.  Over 8000 people focused on curing and treating MS will attend including Dr. Barry Singer and Dr. Mark Tullman. New therapies including some expected to be FDA-approved in 2016 will be discussed.  The first MS treatment to work in primary progressive multiple sclerosis trials with be reviewed.  Progress on myelin repair strategies will be highlighted including research at our center.  Options for improving MS symptoms and quality of life will be addressed.  A question and answer session will follow.  Speakers include Barry Singer MD,  Mark Tullman MD and Heather Popham, NP-C.

The FREE program is sponsored by Missouri Baptist Medical Center and will be held Thursday October 29, 2015 at the St. Louis Frontenac Hilton at 6:30 PM.  Light refreshments will be served.

REGISTER at 314-996-LIFE.    Love to see you there!

Sep 15 2014 Join us for Multiple Sclerosis Breakthroughs Program

Your Invited!  Come to our program on the latest MS treatments along with strategies to reduce MS symptoms and improve quality of life. Groundbreaking research from the world’s largest annual international MS conference will be presented.  Hear about potential future preventative therapies and treatments to repair myelin in attempt to restore function in individuals living with MS.  A question and answer session will follow the presentation.  FREE.  Refreshments will be served.  Presenters: Barry Singer, MD; Mark Tullman, MD and Heather Popham, NP.  Sponsored by Missouri Baptist Medical Center.

Thursday, Oct 30, 2014.  6:30 PM to 8:30 PM. St. Louis Frontenac Hilton.  1355 South Lindbergh.



Aug 24 2014 BJC Today Article: Doc gets down and dirty for his patients

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Feb 11 2014 Watch Dr. Singer’s TV interview: Lemtrada’s FDA decision

On Feb 7,  Barry Singer, MD and a person living with MS that participated in a Lemtrada trial were interviewed regarding the impact of the FDA denial of Lemtrada (alemtuzumab).  The treatment demonstrated a reduction of new attacks by 49-55% compared to Rebif in two clinical trials.  Dr. Singer addresses why the FDA made their decision, but talks about the appeal process for trying to reverse the decision.  Lemtrada has recently been approved for use in Europe, Canada and Australia.  Learn how to join a petition to the FDA to get Lemtrada approved for use in the United States.



Dec 20 2013 Share YOUR MS Story:







Dr. Barry Singer just launched!

The website gives voice to those living with MS.   MS cannot stop the spirit of those living with the disease. Submit your own post or read the awesome, inspiring and heartfelt posts.

The website is a collage of video, pictures, tweets and instagrams.

Use #ICanWithMS to send tweets or instagrams directly to site from your Twitter or Instagram account.



Oct 14 2013 Can Remyelination Reverse Disability?

How can disability from multiple sclerosis be reversed?  An exciting approach is remyelination,  a process in which new myelin is made.   The myelin coating on nerve cells allows messages to travel rapidly such as from the brain down the spinal cord.  Loss of the myelin coating can delay or block the messages getting to where they need to go.  Chronic myelin loss may actually cause some nerve cells to slowly die. 

Myelin is formed from cells called oligos (short for oligodendrocytes) that wrap around and around multiple nerve cells.  In MS, the immune system attacks myelin, causing temporary or permanent myelin loss.

In the human brain, 5-8% of cells have the potential to grow-up to be myelin-making oligos.   These immature cells are called OPCs (oligodendrocyte precursor cells).   So how do we get these OPCs to create new myelin and repair old damage?  

One step is trying to make more of these OPC s.   Growth factors, such as PDGF-AA, can stimulate the OPCs to divide and multiply.   Another approach is attracting the potential myelin-making cells into the MS plaques.  Semaphorin- 3F, for example, is a protein that can attract OPCs to areas of loss of myelin. Chemokines are other compounds that can help OPCs to move into a plaque for remyelination.

Removing factors that block remyelination is a another way to try to repair myelin.   High levels of LINGO-1 , for example, prevent OPCs from maturing and making myelin.  An antibody to LINGO-1 allowed for remyelination to occur in animal models and is now being tested in human clinical trials.   Other antibody therapies are being developed that stimulate remyelination in animal models .  Whether these strategies will be effective and/or safe remains to be determined.

Research has led the way to effective treatments that reduce the immune attack against the brain, spinal cord and optic nerves.  However, multiple sclerosis still causes increasing disability for too many people.  While a cure is paramount, myelin-repair strategies will be an important frontier over this decade in the attempt to restore function.

Aug 31 2013 MS Breakthroughs Program

Your Invited!   FREE educational program on the latest advances only 5 days after the most important global multiple sclerosis meeting called ECTRIMS.  Info on new potential treatments will be highlighted.  Breakthroughs in myelin repair will be discussed.  Dr. Barry Singer, Dr. Mark Tullman and Heather Popham, NP-C  from The MS Center in Innovations in Care at Missouri Baptist will be presenting.  Missouri Baptist Medical Center sponsors this annual research program.

DETAILS:    Thursday October 10, 2013 6:30 PM to 8:30 PM

St. Louis Frontenac Hilton, 1335 South Lindbergh Blvd., Saint Louis, Missouri, 63131, USA

REGISTER:  314 996-LIFE   (314-996-5433)  or or toll-free (800) 392-0936.

(Registration telephone lines open 8 AM to 6 PM Monday-Friday)

Refreshments will be served.

Hope to see you there!





Jul 7 2013 Muckfest 2013: A Muddy Blast for MS

On Saturday July 6,  Dr. Singer’s team, the Filthy Five (actually four this year) returned for our fourth year for the Muckfest.    We completed the 5 mile military-style  obstacle course in the MUD and raised greater than $8000 for the Gateway Chapter of the National Multiple Sclerosis Society.   Over 2500 runners participated.   The cool mud helped with the >90 degree F weather!  Thanks to all who participated, volunteered and donated!

CLICK PICTURE for bigger view.

Dr. Barry Singer is now on TWITTER with the latest news in MS. 


Jun 22 2013 Curious about the oral MS meds?

We posted a new table with some answers regarding the oral MS medications including Gilenya (fingolimod), Aubagio (teriflunomide) and Tecfidera (BG-12).    The printable or downloadable pdf table gives the breakdown on how the medications work, how well they work and potential risks.  It’s an exciting time to have more treatment options for people to chose from to help control their disease while maximizing quality of life.

New ORAL MS Treatment Table


Dr. Barry Singer is also jumping into the world of TWITTER!   SIGN up to follow his latest tweets on new MS breakthroughs, living well with MS advice, and other “hot off the press info.”  The MS Center for Innovations in Care at Missouri Baptist Medical Center (MOBAP) updates will be tweeted as well.

Dr. Singer on TWITTER