MS Living Well Podcast. Secondary Progressive MS: Next Chapter

Progressive symptoms are a common part of the multiple sclerosis (MS) journey, affecting nearly 50% of individuals at some point in their disease course. These symptoms can present in various ways, including worsening mobility, balance issues, cognitive changes, and sensory disturbances. Because progression often stems from a combination of underlying factors, effective treatment typically involves a multidisciplinary approach—combining lifestyle changes, therapy, and medication.

In this episode of MS Living Well, we take a deep dive into the diagnosis and management of progressive MS symptoms. The discussion begins with a look at the latest clinical data on available and emerging treatment options, then transitions into real-world insights on patient care in the clinic.

Jameson Holloman MD

We are also thrilled to introduce our new co-host for this season: Dr. Jamie Holloman! Dr. Holloman completed a three-year MS fellowship at the Cleveland Clinic following his neurology residency at Washington University. He recently joined the MS Center for Innovations in Care, bringing fresh perspective and enthusiasm to the MS Living Well team.

Barry Singer MD

In this episode, Dr. Holloman interviews his colleague and mentor, Barry Singer MD, about current and upcoming therapies for disease progression in MS. Their conversation includes a spotlight on tolebrutinib, an experimental medication currently under expedited FDA review for the treatment of secondary progressive MS.

Christopher LaGanke MD

Later, Dr. Holloman speaks with Christopher LaGanke MD, founder of North Central Neurology Associates in Cullman, Alabama—a leading site for MS clinical trials. Dr. LeGanke shares his clinical approach to managing progressive symptoms. A dedicated physician and researcher, Dr. LeGanke received his medical degree from Meharry Medical College and completed his training at the University of Alabama, including a two-year neuroimmunology fellowship in MS. He also founded the Joanne P. LaGanke MS Center, named in honor of his mother.

Join us for an insightful conversation that blends cutting-edge science with compassionate, practical care!

This episode is sponsored by TG Therapeutics.