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MS Living Well Podcast: Hormones and Multiple Sclerosis

Feb 27 2024

Sex hormones, such as estrogens and testosterone, affect each individual’s journey living with multiple sclerosis. While both genders face equal MS risk before puberty and after menopause, women experience up to three times higher risk during their reproductive years. Pregnancy generally brings less relapses, potentially attributed to high estriol levels. However, navigating treatment decisions well while trying to conceive and after delivery requires finesse and expertise. Equip yourself with the latest women’s health info regarding MS, covering topics from birth control and fertility treatments to menopause and osteoporosis.

Testosterone has important anti-inflammatory and neuroprotective benefits in multiple sclerosis.  Nevertheless, men are at higher risk for disability progression then women. Declining testosterone levels over time (called andropause) and Y chromosome genes may tilt the scales towards disability. Listen to current testosterone research including potential remyelination benefits.

This podcast episode is sponsored by TG Therapeutics.

Barry Singer MD, Director of The MS Center for Innovations in Care, interviews:

Maria Houtchens MD

Maria Houtchens MD, the founding director of the Women’s Health Program at the Brigham MS Center in Boston and Associate Professor of Harvard Medical School. She also is the founder of PREG-MS (a collaborative New England MS pregnancy registry) and a founding board member of the MS-CERCH, an international consortium of the MS Centers of Excellence in Reproductive and Child Health. She completed both her residency and neuroimmunology fellowship at Brigham and Women’s Hospital.  As a global leader in health related to women living with multiple sclerosis, Dr. Houtchens continues to research, publish and direct global educational efforts.

Jorge Correale MD

Jorge Correale MD, Head of Neuroimmunology and Demyelinating Diseases at the Dr. Raúl Carrea Institute of Neurological Research in Buenos Aires since 1997. Dr. Correale completed neuroimmunology fellowships at Karolinska Institute in Stockholm and the University of Southern California. He is currently the Deputy Chair of the MS International Federation. He previously served as Vice President and President of the Argentine Neurological Society (2008-2012) and President of LACTRIMS (2014-2016). Dr. Correale has authored greater than 250 articles and greater than 50 chapters. His research is focused on the role of environmental factors and sex hormones on the development and progression of multiple sclerosis.

BY: Barry Singer, MD DATE: February 27, 2024 TOPIC: Podcasts